Massimo Fioranelli
 
 
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Arrhythmias
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DEFINITION OF ATRIAL FIBRILLATION


Atrial fibrillation (AF) is a supraventricular tachyarrhythmia characterised by uncoordinated atrial activation with consequent deterioration of mechanical function.
On the ECG, rapid oscillations, or fibrillatory waves that vary in amplitude, shape, and timing, replace consistent P waves. There is an irregular ventricular response that is rapid when conduction is intact.


Atrial Fibrillation



PREVALENCE OF ATRIAL FIBRILLATION
  • AF is the most common sustained cardiac arrhythmia
  • 6.8 Million patients have AF in the EU and the US
  • AF prevalence is expected to increase by =2.5-fold by 2050 in the US
  • The lifetime risks for development of AF is 1 in 4 for patients =40 years and this risk remains high (1 in 6), even in the absence of underlying disease


CONSEQUENCE OF ATRIAL FIBRILLATION
  • At least 33% of AF patients could be asymptomatic
  • Holter and transtelephonic monitoring studies have demonstrated that asymptomatic episodes of paroxysmal AF are 10-12 times more frequent than symptomatic episodes
  • AF episodes may go unnoticed if asymptomatic, yet could still have long term deleterious consequences for the patient





Ventriculat Tachycardia







Ventricular Fibrillation







 

 

 

 
 
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